Targeting CCL5 in inflammation
نویسندگان
چکیده
منابع مشابه
Platelet CCL5 links acute coronary syndrome and vascular inflammation.
http://dx.doi.org/10.1160/TH14-11-0910 Thromb Haemost 2015; 113: 1079 Insight on ▶Blanchet et al. Thromb Haemost 2014; 112: 1277-1287. Initiation and progression of atherosclerosis, a chronic inflammatory process of the arterial wall that ultimately leads to ischaemic events (e.g. myocardial infarction, stroke), is mediated by a number of extracellular and cellular factors including blood plate...
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Of the definitions listed in the International Statistical Classification of Diseases and Related Health Problems, tenth revision (ICD-10), two disease descriptions can be found together: "idiopathic aseptic bone necrosis" and "avascular bone necrosis." The relevant literature on both the conditions abbreviates both as "aseptic ischemic osteonecrosis in the jawbone" (AIOJ). To shed light on the...
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While blocking tumor growth by targeting autophagy is well established, its role on the infiltration of natural killer (NK) cells into tumors remains unknown. Here, we investigate the impact of targeting autophagy gene Beclin1 (BECN1) on the infiltration of NK cells into melanomas. We show that, in addition to inhibiting tumor growth, targeting BECN1 increased the infiltration of functional NK ...
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ژورنال
عنوان ژورنال: Expert Opinion on Therapeutic Targets
سال: 2013
ISSN: 1472-8222,1744-7631
DOI: 10.1517/14728222.2013.837886